SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Sinonimi:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
Specie:
Human SMARCA4 (6597), Mouse Smarca4 (20586), Rat Smarca4 (171379), dog SMARCA4 (476710), sheep SMARCA4 (101116565), domestic cat SMARCA4 (101097046), Zebrafish smarca4 (353295), chicken SMARCA4 (395932), cow SMARCA4 (414274), naked mole-rat Smarca4 (101700987)
ID UniProtKB:
ID gene:
- Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-BRG1 Antibody, clone 1N12, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SNF2β/BRG1 Antibody, serum, Upstate®,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-SMARCA4 Antibody, clone 20C3.2, clone 20C3.2, from mouse,
Reattività con
human, rat
Applicazione
immunocytochemistry
western blot
western blot
Anti-SMARCA4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-BRG1/SMARCA4 Antibody, clone 20C3.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, rat
Applicazione
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
esiRNA
N° Catalogo
Descrizione
Specie