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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Sinonimi:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Specie:
ID UniProtKB:
ID gene:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reattività con
human
Applicazione
western blot
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Reattività con
rat
Applicazione
western blot
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, guinea pig, horse, human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Flecainide acetate salt, ,
Specie
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Specie
human

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
Lamotrigine, ≥98%, powder,
Specie
rat, human
Cocaine free base, ,
Specie
mouse, rat, human
Carbamazepine, powder,
Specie
rat, human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human SCN5A,
Specie
human