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Merck

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Sinonimi:
ROCK-II
Specie:
ID UniProtKB:
ID gene:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-ROCK2 Antibody, clone 1B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
canine, feline, horse, human, monkey, mouse, rat
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-ROCK2, (C-terminal) antibody produced in mouse, clone 1E12, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Y-27632, ≥98% (HPLC),
Specie
human
Adenine, ≥99%,
Specie
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
Specie
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Specie
human, rat, mouse

Proteins

Numero di prodotto
Descrizione
Specie
ROCK2 (5-554), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ROCK2,
Specie
human