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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Sinonimi:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Specie:
ID UniProtKB:
ID gene:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

N° Catalogo
Descrizione
Specie
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
Reattività con
mouse
Applicazione
immunohistochemistry
western blot
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-Cox2 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Carprofen, ≥97% (HPLC),
Specie
human
Aceclofenac, ≥98% (HPLC),
Specie
human
Celecoxib, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Celecoxib, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Etoricoxib, VETRANAL®, analytical standard,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ptgs2,
Specie
mouse
MISSION® esiRNA, targeting human PTGS2,
Specie
human