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Merck

P2RX1

purinergic receptor P2X, ligand-gated ion channel, 1

Sinonimi:
P2X1
Specie:
Human P2RX1 (5023), Mouse P2rx1 (18436), Rat P2rx1 (25505), Domestic Rabbit P2RX1 (100350587), domestic cat P2RX1 (101091060), Horse P2RX1 (100060689), cow P2RX1 (514898), domestic guinea pig P2rx1 (100727772), sheep P2RX1 (101101902), Zebrafish p2rx1 (387296) ...Più
ID UniProtKB:
P51575, Q9UK84
ID gene:
  • Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
  • Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
  • Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
  • Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
  • Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
  • cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
  • sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1
  • Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
  • chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
  • dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
  • naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
M6517
α,β-Methyleneadenosine 5′-triphosphate lithium salt, ≥93% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
244813
Reactive Blue 4, Dye content 35 %,
Specie
rat
N8652
NF 023 hydrate, ≥98% (HPLC), solid,
Specie
human
P178
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
AV35105
Anti-P2RX1 antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
dog, horse, human
Applicazione
immunohistochemistry
western blot
SAB1410866
Anti-P2RX1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
HPA057678
Anti-P2Rx1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
P7857
Anti-P2X1 Purinergic Receptor antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reattività con
human, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
S2671
Suramin sodium salt, ≥98% (TLC),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU015831
MISSION® esiRNA, targeting human P2RX1,
Specie
human
EMU053741
MISSION® esiRNA, targeting mouse P2rx1,
Specie
mouse