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Merck

IGF1R

insulin-like growth factor 1 receptor

Sinonimi:
CD221, IGFIR, IGFR, JTK13
Specie:
ID UniProtKB:
ID gene:
  • Human(3480) Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
  • Mouse(16001) insulin-like growth factor I receptor
  • Rat(25718) insulin-like growth factor 1 receptor
  • domestic guinea pig(100734840) insulin-like growth factor 1 receptor
  • chicken(395889) insulin-like growth factor 1 receptor
  • naked mole-rat(101710224) insulin-like growth factor 1 receptor
  • Horse(100055698) insulin-like growth factor 1 receptor
  • domestic cat(100500937) insulin-like growth factor 1 receptor
  • cow(281848) insulin-like growth factor 1 receptor
  • dog(442951) insulin-like growth factor 1 receptor
  • sheep(443002) insulin-like growth factor 1 receptor

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ELISA

N° Catalogo
Descrizione
Specie
Human IGF-I R ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-fosfo-IGF-1R (Tyr1161/ Tyr1165/ Tyr1166), from rabbit, purified by affinity chromatography,
Reattività con
xenopus, chicken, human, mouse, pig, porcine, rat, zebrafish
Applicazione
cell based assay
western blot
Anti-IGF1R antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, horse, human, pig, sheep
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-IGF-1R β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anti-IGF1R (Ab-1161) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-IGF1R (pTyr1161) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Picropodophyllotoxin, ≥96% (HPLC), powder,
Specie
human
I-OMe-Tyrphostin AG 538, solid,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt, ≥98% (HPLC), lyophilized powder,
Specie
human
Insulin-like Growth Factor-I Receptor human, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
human
IGF-IR (δ1-958) Protein, active, 20 µg, Active, N-terminal His6-tagged, recombinant human IGF-IR residues 959-end, for use in Kinase Assays.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human IGF1R,
Specie
human
MISSION® esiRNA, targeting mouse Igf1r,
Specie
mouse

Small Molecule - Substrate

N° Catalogo
Descrizione
Specie
IGF-IRtide, Substrate for in vitro IGF-1R kinase assays.,
Specie
human