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Merck

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Sinonimi:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Specie:
ID UniProtKB:
ID gene:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
Reattività con
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
Applicazione
western blot
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey
Applicazione
affinity binding assay
immunohistochemistry

western blot

Cell Lines

N° Catalogo
Descrizione
Specie
CypExpress Aromatase, ,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Letrozole, ≥98% (HPLC),
Specie
human
Exemestane, ≥98% (HPLC),
Specie
human
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Formestane, solid,
Specie
human
Letrozole, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
DL-Aminoglutethimide, ,
Specie
human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Cyp19a1,
Specie
mouse
MISSION® esiRNA, targeting human CYP19A1,
Specie
human