KIAA0406, Protein SMG10, TEL2-interacting protein 1 homolog, Tel two interacting protein 1, Tel2 interacting protein 1 homolog (S. pombe), nonsense mediated mRNA decay factor, nonsense mediated mRNA decay factor (C. elegans), smg-10, smg-10 homolog
The epitope recognized by PLA0280 maps to a region between residue 1 and 50 of human Tel2 Interacting Protein 1 using the numbering given in entry NP_055472.1 (GeneID 9675).
TEL2-interacting protein 1 homolog (TTI1) promotes assembly, stabilizes, and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43156].
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