Skip to Content
Merck
All Photos(1)

Key Documents

P1742

Sigma-Aldrich

Prealbumin from human plasma

lyophilized powder

Synonym(s):

Thyroxine binding prealbumin, Transthyretin

Sign Into View Organizational & Contract Pricing

Select a Size

0.5 MG
HUF 82,200.00
1 MG
HUF 143,000.00
5 MG
HUF 571,000.00

HUF 82,200.00


Please contact Customer Service for Availability

Request a Bulk Order

Select a Size

Change View
0.5 MG
HUF 82,200.00
1 MG
HUF 143,000.00
5 MG
HUF 571,000.00

About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25

HUF 82,200.00


Please contact Customer Service for Availability

Request a Bulk Order

biological source

human plasma

Quality Level

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

technique(s)

immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable

impurities

Infectious agents, tested

solubility

H2O: soluble 1 mg/mL

ε (extinction coefficient)

13.5 at 280 nm at 1%

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... TTR(7276)

Looking for similar products? Visit Product Comparison Guide

General description

Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver.[1] It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.[2]

Application

Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.[3]
Prealbumin from human plasma has been used as a positive control in immunoprecipitation[4] as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.[5]

Biochem/physiol Actions

Human prealbumin has been observed in carcinoid tumors.[1]
Prealbumin levels are indictors of malnutrition and may be modulated during inflammation.[6] It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis.[7] Low levels of prealbumin poses high risk to heart failure (HF).[8]

Packaging

Package size based on protein content

Physical form

Lyophilized powder containing sodium phosphate and NaCl

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J P Hegmann
Behavior genetics, 9(3), 165-175 (1979-05-01)
Behavioral and physiological scores from 697 mice sampled from lines at various times during their response to bidirectional selection for divergent caudal nerve conduction velocity suggest broad-reaching behavioral effects of the gene differences among lines. Sciatic nerve conduction velocity differences
David Adams et al.
Presse medicale (Paris, France : 1983), 41(9 Pt 1), 793-806 (2012-02-22)
The treatment of familial amyloid polyneuropathies (FAP) is complex and requires a neurological and cardiological multidisciplinary coverage. It includes specific treatments to control the progression of the systemic amyloidogenesis, the symptomatic treatment of the peripheral and autonomic neuropathy (digestive, urinary
Gen Sobue
Rinsho shinkeigaku = Clinical neurology, 43(11), 769-774 (2004-05-22)
A nationwide study of CMT and FAP has been performed. In FAP TTR Met30 families with late onset, neuropathy showed male preponderance, low penetrance, little relationship to endemic foci, sensorimotor symptoms beginning distally in the lower extremities with disturbance of
Serum albumin and prealbumin in calorically restricted, nondiseased individuals: a systematic review
Lee JL, et al
The American Journal of Medicine, 128(9), 1023-e1-1023-e1 (2015)
K Tashima et al.
Journal of the neurological sciences, 171(1), 19-23 (1999-11-24)
Since 1990, liver transplantation for familial amyloidotic polyneuropathy (FAP) has been carried out world-wide, and the outcome of the procedure seems to be promising. FAP is inherited systemic disease caused by mutated transthyretin. The most common cause is the valine

Questions

1–6 of 6 Questions  
  1. How long does prealbumin from human plasma (product P1742) remain stable after being dissolved in water, and at what temperature should this solution be stored?

    1 answer
    1. Stock solutions are stable for up to 2 weeks when stored refrigerated at 4°C and up to 6 months when stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles.

      Helpful?

  2. What is the molecular weight of Product P1742, Prealbumin from human plasma?

    1 answer
    1. The molecular weight has been reported to be 54,980 Daltons. Referece: The Plasma Proteins, 2nd edition (1975) p. 60.

      Helpful?

  3. What is the solubility of Product P1742, Prealbumin from human plasma?

    1 answer
    1. This product is soluble in water at 1mg/mL.

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. What is the volume from which Product P1742, Prealbumin from human plasma, is lyophilized from?

    1 answer
    1. The starting volume is lot specific. Please contact Technical Service to obtain the exact volume of your lot of interest.

      Helpful?

  6. What is the purity of Product P1742, Prealbumin from human plasma?

    1 answer
    1. Information about purity can be found on the lot specific certificate of analysis.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service