Toxicological sciences : an official journal of the Society of Toxicology, 79(1), 106-111 (2004-01-23)
Kava herbal supplements have been recently associated with acute hepatotoxicity, leading to the ban of kava products in approximately a dozen countries around the world. It is suspected that some alkaloids from aerial kava may have contributed to the problem.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 10(4), 309-317 (2003-06-18)
Two unique evidence that cancer incidence rates in Fiji were unusually low, compared with those of another Pacific islands and that green tea beverage is an acknowledged cancer preventive in Japan, allowed us to study a local beverage in Fiji
Journal of pharmacological sciences, 118(4), 447-454 (2012-04-19)
The nuclear factor-κB (NF-κB) transcription factors control many physiological processes including inflammation, immunity, and apoptosis. In our search for NF-κB inhibitors from natural resources, we identified yangonin from Piper methysticum as an inhibitor of NF-κB activation. In the present study
Phytomedicine : international journal of phytotherapy and phytopharmacology, 11(4), 285-294 (2004-06-10)
The effects of the herbal product kava (Kava kava, 'Awa, Yaqona, Piper methysticum) on human P450 isoforms were studied in vitro using both cDNA-expressed human enzymes and cryopreserved human hepatocytes. Increasing concentrations of an ethanolic extract of dried kava root
Phytomedicine : international journal of phytotherapy and phytopharmacology, 9(3), 263-267 (2002-06-06)
To evaluate the effects of intrinsic (natural) fluorescence and quenching as confounding variables in fluorescence-based enzyme inhibition assays of natural products, we measured the fluorescence and quenching properties of 25 components of popular herbal products. The analyses were performed under
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