Recognizes a single 27 kD band in Western blots and is reactive against Nef in immunoprecipitation and immunofluorescent assays. The reactive epitope maps to the COOH terminus of the full length Nef protein. MAB899 does not recognize Nef from HIV-1SF2.
Application
Anti-HIV Nef Antibody, clone AG11 is an antibody against HIV Nef for use in ELISA, IF, IH, IP & WB.
Research Category Infectious Diseases
Research Sub Category Infectious Diseases - Viral
Western blot (1:1000) ELISA (1:100000) when tested against recombinant HIV-1IIIB Nef. For extensive dilution, protein containing or other stabilizing medium should be used. Immunofluorescence Immunoprecipitation Optimal working dilutions must be determined by end user.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M PB + 0.25 M NaCl + 0.1% Na Azide, pH = 7.6
Storage and Stability
Maintain at 2° to 8°C for up to 12 months from date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Head and neck pathology, 4(2), 97-105 (2010-03-25)
Oncogenic human papillomaviruses (HPVs) are associated with oropharyngeal squamous cell carcinoma (SCC). Infection with human immunodeficiency virus (HIV) increases susceptibility to opportunistic infections and viral-promoted cancers. The prevalences of HPV, herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human herpesvirus-8
Several investigators have proposed that autoimmunity may be induced by idiotype-antiidiotype antibody networks. It is generally assumed that the antiidiotype is produced in response to the idiotype, and therefore that autoimmune diseases have single antigenic initiators. The theory of multiple-antigen-mediated
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