Tripartite motif-containing protein 5 (TRIM5), also known as the RING finger protein 88 (RNF88), is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. The TRIM5 delta isoform has been shown to colocalize with BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells serving as a scaffold for the assembly of endogenous BTBD proteins.
Immunogen
KLH-conjugated linear peptide corresponding to human TRIM5 delta.
Application
Anti-TRIM5 delta Antibody is a highly specific rabbit polyclonal antibody, that targets Tripartite motif-containing protein 5 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected TRIM5 delta in mouse brain tissue.
Research Category Inflammation & Immunology
Research Sub Category Immunoglobulins & Immunology
Quality
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 delta in 15 µg of mouse brain tissue lysate.
Target description
~25 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control Mouse brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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