QBD10401

NHS-dPEG^®₄-( m-dPEG^®₁₂)₃-ester

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₁₀₈H₂₀₆N₆O₅₂
• CAS Number: 1334178-03-8
• Molecular Weight: 2420.80
• MDL number: MFCD16621418
• UNSPSC Code: 12352108
• PubChem Substance ID: 329823925
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• polymer architecture: shape: branched; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: N1(C(=O)CCC1=O)OC(=O)CCCC(=O)NCCOCCOCCOCCOCCC(=O)NC(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
• InChI: 1S/C108H206N6O52/c1-123-25-28-131-41-44-139-55-58-145-67-70-151-79-82-157-91-94-160-88-85-154-76-73-148-64-61-142-52-49-136-38-33-128-22-14-110-101(116)9-18-163-97-108(113-104(119)12-17-126-31-36-134-47-48-135-37-32-127-21-13-109-100(115)5-4-6-107(122)166
• InChI key: VOPFWBJWEJMWRQ-UHFFFAOYSA-N

Description

Features and Benefits

NHS-dPEG^®₄-(m-dPEG₁₂)₃-ester is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. These dPEG^® products consist of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG^® branches. All of these dPEG^® products are hydrophilic, non-immunogenic, single molecular weight compounds. N-hydroxysuccinimide (NHS) group reacts with free amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable