Electronic effects and the bond network are the two factors that cause out-of-center distortions in octahedral d(0) transition metal oxide fluoride anions. Overlap between filled oxide p orbitals and vacant cation d orbitals results in strong, short metal-oxide bonds causing
A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3alpha).
Synthesis of (R)-(+)-methyl 3-amino-3-(5-hydroxy-2-pyridinyl) propanoate, an analog of l-azatyrosine.
Pyridinols and pyridinamines are important intermediates with many applications in chemical industry. The pyridine derivatives are in great demand as synthons for pharmaceutical products. Moreover, pyridines are used either as biologically active substances or as building blocks for polymers with
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