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A1345

Sigma-Aldrich

Antioxidant Supplement (1000×)

Antioxidant Supplement (1000×)
1 of 1 reviewers received a sample product or took part in a promotion

liquid, sterile-filtered, suitable for cell culture

Sinónimos:

Antioxidant Solution

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About This Item

UNSPSC Code:
12352205
NACRES:
NA.75
En este momento no podemos mostrarle ni los precios ni la disponibilidad

sterility

sterile-filtered

Quality Level

400

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

Categorías relacionadas

General description

Antioxidant Supplement (1000×) is a proprietary medium supplement specially formulated to boost cell growth for enhanced viral and protein expression. It may be used in combination with Polyamine Supplement (P 8483).
One mL supplements 1 liter of medium.

Application

Antioxidant Supplement (1000×) has been used:

  • as a component of the extender media for dilution of sperm samples during cryopreservation[1]
  • for long term culture of human-induced pluripotent stem (iPS) cells[2]
  • as a component of the immortalization media used for culturing, cloning and expansion of clones for making immortalized cell lines from embryonic mouse kidney[3]

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000381132
0000381132
SLCN8287
SLCM2928
SLCH3774

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E Cabrita et al.
Animal reproduction science, 125(1-4), 189-195 (2011-04-13)
During cryopreservation, dilution in the extender media reduces the seminal plasma constituents being cells more vulnerable to oxidative stress. Vitamins (C and E) and the amino acids taurine and hypotaurine are powerful antioxidants naturally present in seminal plasma. Whether their
Lan Luo et al.
Scientific reports, 4, 3779-3779 (2014-01-22)
Effects of antioxidants on the quality and genomic stability of induced pluripotent stem (iPS) cells were investigated with two human iPS cell lines (201B7 and 253G1). Cells used in this study were expanded from a single colony of each cell
Michael R Duggan et al.
Cell death discovery, 7(1), 60-60 (2021-03-28)
Despite increasing numbers of aged individuals living with HIV, the mechanisms underlying HIV-associated neurological disorders (HANDs) remain elusive. As HIV-1 pathogenesis and aging are characterized by oxidative stress as well as altered protein quality control (PQC), reactive oxygen species (ROS)
Kendall Mitchell et al.
BMC neuroscience, 17(1), 80-80 (2016-12-03)
Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post-operative pain in patients treated with BMP-2 has
Amanda McQuade et al.
Nature communications, 11(1), 5370-5370 (2020-10-25)
The discovery of TREM2 as a myeloid-specific Alzheimer's disease (AD) risk gene has accelerated research into the role of microglia in AD. While TREM2 mouse models have provided critical insight, the normal and disease-associated functions of TREM2 in human microglia
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Questions

1–2 of 2 Questions  

  1. Please let me know the ingredients and their concentrations of the product.

    1 answer

    1. The formulation of this product is considered proprietary.

      Helpful?

  2. Does the antioxidant supplement A1345 contain components of animal/human origin?

    1 answer

    1. Product A1345 is free of animal components. This is a specification that is presented on the Certificate of Analysis.
      To download a Certificate, or to see a sample Certificate, please navigate to the link below:
      https://www.sigmaaldrich.com/product/sigma/a1345#product-documentation

      Helpful?

Reviews

1 of 1 reviewers received a sample product or took part in a promotion

Active Filters

  1. London
    • Review 1
    • Vote 1
    5 out of 5 stars.

    Effective supplement

    Works well for optogenetic experiments to protect cells from free radical damage produced by light exposure

    Helpful?

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