69453

L-Homocysteine

≥98.0% (NT)

• Sinónimos: (S)-2-Amino-4-mercaptobutyric acid
• Fórmula lineal: HSCH₂CH₂CH(NH₂)COOH
• Número de CAS: 6027-13-0
• Peso molecular: 135.18
• EC Number: 227-891-0
• MDL number: MFCD00151320
• UNSPSC Code: 12352204
• PubChem Substance ID: 329761669
• NACRES: NA.32

Propiedades

• product name: L-Homocysteine, ≥98.0% (NT)
• Quality Level: 100
• assay: ≥98.0% (NT)
• form: powder
• optical activity: [α]/D 25.5±1.5°, c = 1 in 1 M HCl
• color: white
• mp: 263-265 °C
• application(s): cell analysis
• relevant disease(s): Alzheimer′s disease
• storage temp.: −20°C
• SMILES string: N[C@@H](CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
• InChI key: FFFHZYDWPBMWHY-VKHMYHEASA-N

Descripción

General description

L-homocysteine is used to diagnose homocystinuria.

Application

L-homocysteine has been used as a supplement in cell culture media.

Biochem/physiol Actions

Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable