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30170

Sigma-Aldrich

L-Cysteic acid monohydrate

≥99.0% (T), suitable for LC/MS

Sinónimos:

(R)-2-Amino-3-sulfopropionic acid

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About This Item

Fórmula lineal:
HO3SCH2CH(NH2)CO2H·H2O
Número de CAS:
23537-25-9
Peso molecular:
187.17
Beilstein:
3714036
Número MDL:
MFCD00149544
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
24858207
NACRES:
NA.26

Nombre del producto

L-Cysteic acid monohydrate, ≥99.0% (T)

Nivel de calidad

200

Ensayo

≥99.0% (T)

Formulario

powder or crystals

actividad óptica

[α]20/D +7.5±0.5°, c = 5% in H2O

técnicas

LC/MS: suitable

color

white to faint yellow

mp

267 °C (dec.) (lit.)

solubilidad

H2O: soluble

aplicaciones

peptide synthesis

cadena SMILES

[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1

Clave InChI

PCPIXZZGBZWHJO-DKWTVANSSA-N

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Categorías relacionadas

Aplicación

Internal standard for amino acid analysis.

Acciones bioquímicas o fisiológicas

L-Cysteic acid is a sulfur containing aspartate analogue that may be used as a competitive inhibitor of the bacterial aspartate:alanine antiporter (AspT) exchange of aspartate and in other aspartate biological systems. L-Cysteic acid is used in monomeric surfactant development.
L-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCL4461
BCCH3336
BCCF8492
BCCF8140
BCCF7794

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B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
A E Kingston et al.
Neuropharmacology, 37(3), 277-287 (1998-07-29)
Comparison of the pharmacological effects of a range of sulphur-containing amino acids on human mGluR1alpha and mGluR5a has been undertaken. cDNAs of each mGluR were transfected into a Syrian hamster tumour cell line AV12-664 that was previously transfected with the
Naoko Arashida et al.
Analytica chimica acta, 954, 77-87 (2017-01-14)
Amino acids and their related metabolites play important roles in various physiological processes and have consequently become biomarkers for diseases. However, accurate quantification methods have only been established for major compounds, such as amino acids and a limited number of

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