901466

Mes-Umemoto reagent

≥95%

• Sinónimos: Dimesityl(trifluoromethyl)sulfonium trifluoromethanesulfonate, MacMillan trifluoromethylation reagent, dMesSCF3 reagent
• Fórmula empírica (notación de Hill): C₂₀H₂₂F₆O₃S₂
• Número de CAS: 1895006-01-5
• Peso molecular: 488.51
• Número MDL: MFCD31619197
• Código UNSPSC: 12161600
• NACRES: NA.22

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥95%
• Formulario: powder
• idoneidad de la reacción: reagent type: catalyst; reaction type: Photocatalysis
• grupo funcional: fluoro; thioether; triflate
• temp. de almacenamiento: −20°C
• cadena SMILES: FC(F)(F)[S+](c2c(cc(cc2C)C)C)c1c(cc(cc1C)C)C.FC(F)(F)[S](=O)(=O)[O-]
• InChI: 1S/C19H22F3S.CHF3O3S/c1-11-7-13(3)17(14(4)8-11)23(19(20,21)22)18-15(5)9-12(2)10-16(18)6;2-1(3,4)8(5,6)7/h7-10H,1-6H3;(H,5,6,7)/q+1;/p-1
• Clave InChI: HAYTWACXJNSBRL-UHFFFAOYSA-M

Descripción

Aplicación

Under a dual catalytic copper/photoredox manifold, the Mes-Umemoto reagent has been demonstrated by the MacMillan lab to be an excellent reagent for the trifluoromethylation of alkyl halides and aryl halides to yield alkyl-CF₃ and aryl-CF₃ in high yields. In both cases, these reactions exhibit wide substrate scope with good functional group tolerance. More specifically, a variety of 5-membered and 6-membered heteroaryl halides can be readily converted to the corresponding trifluoromethylheteroarenes under mild conditions. To be use in conjunction with supersilanol (902489) and Ir photocatalyst (902217 or 902225).

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Otras notas

A radical approach to the copper oxidative addition problem:Trifluoromethylation of bromoarenes

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable