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792632

Sigma-Aldrich

Isoflurane

Sinónimos:

Isoflurane, 1-Chloro-1-(difluoromethoxy)-2,2,2-trifluoroethane, 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether

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About This Item

Fórmula empírica (notación de Hill):
C3H2ClF5O
Número de CAS:
26675-46-7
Peso molecular:
184.49
Número CE:
247-897-7
Número MDL:
MFCD00066609
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
329768352
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

presión de vapor

238 mmHg ( 20 °C)

Nivel de calidad

100

Formulario

liquid

índice de refracción

n20/D 1.302

bp

48.5 °C

densidad

1.510 g/mL at 25 °C

grupo funcional

chloro
ether
fluoro

temp. de almacenamiento

2-8°C

cadena SMILES

FC(F)OC(Cl)C(F)(F)F

InChI

1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H

Clave InChI

PIWKPBJCKXDKJR-UHFFFAOYSA-N

Información sobre el gen

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GLRA1(2741) , GLRB(2743) , KCNK10(54207) , KCNK18(338567) , KCNK2(3776) , KCNK3(3777) , KCNK9(51305)

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Descripción general

Isofluraneis a fluorinated methyl ether and isomer of enflurane. The Federal DrugAdministration (FDA) has approved it for use as a volatile anesthetic to induceand maintain general anesthesia.

Aplicación

Isoflurane is a volatile anesthetic agent mainly used to study its interaction with the biological system.[1][2]

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H336

Clasificaciones de peligro

STOT SE 3

Órganos de actuación

Central nervous system

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCV7940
MKCW3406
MKCT2138
MKCT6131
MKCS0179

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Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain.
Brambrink AM, et al.
Anesthesiology, 112(4), 834-841 (2010)
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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. マウス実験に用いたいのですが、溶解法を教えてください 250mgを購入させてもらいました。

    1 answer

    1. Isoflurane may be dissolved in a 1:1 solution of DMSO:PBS (pH 7.2). For use as an anesthetic in mouse models, the link below offers an alternative solvent of propylene glycol:
      https://www.research.uky.edu/division-laboratory-animal-resources/open-drop-or-nose-cone-method-isoflurane-anesthesia-mice-and#:~:text=The%20open%2Ddrop%20method%20of,syringe%20with%20the%20plunger%20removed.

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