推荐产品
等级
reagent grade
产品线
Vetec™
方案
99%
表单
powder
mp
>300 °C (lit.)
溶解性
0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
SMILES字符串
NC1=NC(=O)NC=C1
InChI
1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
InChI key
OPTASPLRGRRNAP-UHFFFAOYSA-N
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法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Irene M Kaplow et al.
Genome research, 25(6), 907-917 (2015-04-26)
DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to
Li Shen et al.
Current opinion in cell biology, 25(3), 289-296 (2013-03-19)
5-Methylcytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian cells by the ten-eleven translocation (Tet) family of dioxygenases. While 5mC has been extensively studied, we have just started to understand the distribution and function of 5hmC in mammalian genomes.
Ryan Lister et al.
Science (New York, N.Y.), 341(6146), 1237905-1237905 (2013-07-06)
DNA methylation is implicated in mammalian brain development and plasticity underlying learning and memory. We report the genome-wide composition, patterning, cell specificity, and dynamics of DNA methylation at single-base resolution in human and mouse frontal cortex throughout their lifespan. Widespread
Kian Peng Koh et al.
Current opinion in cell biology, 25(2), 152-161 (2013-03-19)
Changes in cellular phenotypes and identities are fundamentally regulated by epigenetic mechanisms including DNA methylation, post-translational histone modifications and chromatin remodeling. Recent genome-wide profiles of the mammalian DNA 'methylome' suggest that hotspots of dynamic DNA methylation changes during cell fate
Rahul M Kohli et al.
Nature, 502(7472), 472-479 (2013-10-25)
DNA methylation has a profound impact on genome stability, transcription and development. Although enzymes that catalyse DNA methylation have been well characterized, those that are involved in methyl group removal have remained elusive, until recently. The transformative discovery that ten-eleven
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