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Merck

1466696

USP

N-亚硝基甲基氨基丁酸 (NMBA)

United States Pharmacopeia (USP) Reference Standard

别名:

4-[Methyl(nitroso)amino]butanoic acid

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About This Item

经验公式(希尔记法):
C5H10N2O3
CAS号:
分子量:
146.14
分類程式碼代碼:
41116107
NACRES:
NA.24

包裝

pkg of 1 mg

製造商/商標名

USP

應用

pharmaceutical (small molecules)

格式

neat

儲存溫度

−20°C

InChI

1S/C5H10N2O3/c1-7(6-10)4-2-3-5(8)9/h2-4H2,1H3,(H,8,9)

InChI 密鑰

SJLBIPLIGYWGJV-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the USP Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

應用

N-Nitrosomethylaminobutyric Acid (NMBA) USP reference standard is intended for use only as specifically prescribed in the United States Pharmacopoeia.

It is also used to prepare standard, nitrosamine standards stock solution mixture, and sensitivity solutions to determine NMBA impurity in drug substances and drug products (valsartan, irbesartan, and losartan potassium etc) by chromatography according to general chapter <1469> of United States Pharmacopeia.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

其他說明

Sales restrictions may apply.

象形圖

FlameExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

35.6 °F

閃點(°C)

2 °C


分析证书(COA)

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访问文档库

?1469? NITROSAMINE IMPURITIES
United States Pharmacopeia, 46(5) (2021)

商品

大致介绍亚硝胺杂质检测、全球法规以及在样品制备和分析中过滤器选型的主要注意事项。

An overview of nitrosamine impurity testing, worldwide regulations, and key considerations in filter selection for sample preparation and analysis.

This application note describes the LC-MS-based quantitative analysis of known nitrosamine impurities following procedures 1 and 3 as given in USP general chapter <1469>.

相关内容

提供适用USP-NF各论的全面标化的一级标准物质,可用于检验药物成分和剂型、药用辅料、食品和膳食补充剂。

Order from a broad range of highly characterized primary reference standard materials to use with USP-NF monographs for the testing of drug substances & dosage forms, pharmaceutical excipients, food ingredients and dietary supplements.

Accurately detect and quantify trace nitrosamines (NDMA, NDEA, NEIPA, NDIPA, NDBA, etc.) in pharmaceutical drugs using our complete product portfolio and application guides for LC-MS and GC-MS. Order high-quality reference standards, columns, filters & more.

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