1096724

卡莫司汀

United States Pharmacopeia (USP) Reference Standard

• 别名: 1,3-双（2-氯乙基）-1-亚硝基脲, BCNU
• 经验公式（希尔记法）: C₅H₉Cl₂N₃O₂
• CAS号: 154-93-8
• 分子量: 214.05
• MDL號碼: MFCD00057706
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749246
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: carmustine
• 形狀: (Oily liquid to amorphous solid)
• 製造商／商標名: USP
• mp: 30 °C (lit.)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: −20°C
• SMILES 字串: ClCCNC(=O)N(CCCl)N=O
• InChI: 1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
• InChI 密鑰: DLGOEMSEDOSKAD-UHFFFAOYSA-N
• 基因資訊: human ... GSR(2936)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

• Enhancing glioblastoma treatment: Overexpression of Let-7a-3p in U87MG glioblastoma cells enhances chemosensitivity to Carmustine, promoting autophagy and suppressing cell survival, suggesting its role in improving outcomes in glioblastoma multiforme treatment using antineoplastic alkylating compounds (Bahojb Mahdavi et al., 2024).


• Pharmacogenomic profiling in renal cancer: Characterization of mitoribosomal small subunit genes in renal cell carcinoma reveals significant implications for Carmustine′s pharmacogenomic interaction, enhancing understanding of its mechanism in cancer therapy and providing a basis for personalized treatment approaches (Wei et al., 2024).

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H300,H350,H360
• 防範說明: P201 - P280 - P301 + P330 + P331 + P310 - P308 + P313
• 危險分類: Acute Tox. 2 Oral - Carc. 1B - Repr. 1B
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable