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Merck

73035AST

Supelco

Astec® CHIRALDEX G-TA 毛细管GC色谱柱

L × I.D. 50 m × 0.25 mm, df 0.12 μm

别名:

GC column, chiral, gamma-dextran

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About This Item

分類程式碼代碼:
41115710
NACRES:
SB.54

材料

fused silica

描述

GC capillary column

包裝

pkg of 1 ea

參數

-10-180 °C temperature (isothermal or programmed)

β值

500

df

0.12 μm

技術

gas chromatography (GC): suitable

長度 × 內徑

50 m × 0.25 mm

基質活性組

non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase

應用

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
life science and biopharma
personal care
pharmaceutical (small molecule)

柱類型

capillary chiral

分離技術

chiral

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一般說明

Astec® CHIRALDEX G-TA 是第 1 组 CSP(表面相互作用,复合衍生物)的首选。该阶段已被证明是制药行业最广泛选择的阶段,特别是在临床试验的各个阶段中手性中间体和药物研究的分析。在没有包含机制的情况下发生分离,并且通常比大多数手性固定相更快且更有效。G-TA 也被用于分离母体药物对映体及其代谢物。G-TA 对含氧分析物的选择性最高,如醇、二醇和多元醇,作为游离醇和酰基衍生物;胺类作为酰基衍生物;氨基醇、卤素(Cl> Br> F)、氨基酸、羟基酸、内酯、呋喃和吡喃。它对卤化物也具有高选择性。

應用


  • Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation. Application to enzymatic reactions.: This study explores the use of the Astec CHIRALDEX G-TA Capillary GC Column for enantioselective gas chromatographic analysis. The method involves on-line derivatization, enabling the analysis of aqueous samples and applying this technique to enzymatic reactions. This innovative approach highlights the column′s capability in achieving high selectivity and sensitivity for chiral compounds in complex matrices (Mommers et al., 2008).

抗化學/物理腐蝕性

温度限制:
  • -10 °C 至 180 °C 等温和程序的

其他說明

我们提供各种色谱配件,包括分析注射器

法律資訊

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIRALDEX is a trademark of Sigma-Aldrich Co. LLC

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Kinetic resolutions concentrate the minor enantiomer and aid measurement of high enantiomeric purity.
Caron, Gaetan; Tseng, George W.M.; Kazlauskas, R.J.
Tetrahedron Asymmetry, 5 (1), 83-92 (1994)
Asymmetric ring opening of meso-epoxides with B-halobis(2-isocaranyl)boranes 2-dIcr2BX
Roy, Chandra D., Brown, Herbert C.
Tetrahedron Asymmetry, 17 (13), 1931-1936 (2006)
Catalytic asymmetric synthesis of Japonilure and its enantiomer
Xu, Hao, et al.
Tetrahedron Asymmetry, 25 (20-21), 1372-1375 (2014)
Hugo L van Beek et al.
FEBS open bio, 4, 168-174 (2014-03-22)
Enzyme stability is an important parameter in biocatalytic applications, and there is a strong need for efficient methods to generate robust enzymes. We investigated whether stabilizing disulfide bonds can be computationally designed based on a model structure. In our approach
Organocatalysis using protonated 1,2-diamino-1,2-diphenylethane for asymmetric Diels?Alder reaction
Hoon Kim, Kyoung, et al.
Tetrahedron Letters, 46 (36), 5991-5994 (2005)

商品

Chromatographic enantiomeric separation of amino acids, like proline, is described for chiral GC analysis after derivatization.

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