推荐产品
product name
Ascentis® C8 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
材料
stainless steel column
agency
suitable for USP L7
產品線
Ascentis®
特點
endcapped
製造商／商標名
Ascentis®
包裝
1 ea of
標籤範圍
15% Carbon loading
參數
≤70 °C temp. range
400 bar pressure (5801 psi)
技術
HPLC: suitable
LC/MS: suitable
長度 × 內徑
25 cm × 4.6 mm
表面積
450 m2/g
表面覆盖率
4.0 μmol/m2
雜質
<5 ppm metals
基質
fully porous particle
silica gel high purity, spherical
基質活性組
C8 (octyl) phase
粒徑
5 μm
孔徑
100 Å
工作pH值範圍
2-8
應用
food and beverages
分離技術
reversed phase
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相关类别
一般說明
Ascentis 系列色谱柱是 Supelco 科学家推出的第四代 HPLC 色谱柱技术。Ascentis 系列色谱柱是以高纯硅胶为基质，孔径 100Å，硅胶粒径为 3、5 和 10 微米。该色谱柱用于小分子的应用，柱内径可从微径柱（1.0mm 内径）扩展到制备尺寸（50mm 内径）。该系列包括 C18、C8、苯基、Si 和内嵌极性基团相（反相酰胺）。
Ascentis C8 色谱柱重现性好，对极性化合物具有优良的选择性。该键合相在高含水量的流动相和高有机相含量的流动相中均有优良的性能。
Ascentis C8 色谱柱重现性好，对极性化合物具有优良的选择性。该键合相在高含水量的流动相和高有机相含量的流动相中均有优良的性能。
特點和優勢
- 对疏水性分子的保留性极好
- 峰形极佳
- LC-MS 分离流失低
法律資訊
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
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Gastrointestinal stability of venlafaxine was evaluated in vitro in simulated gastric (SGF) and intestinal (SIF) fluids using a stability indicating HPLC method. The method was validated using a 5 microm Ascentis C18 column (150 mm x 4.6 mm) and mobile
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This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
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实验方案
-methylcarbamate 10 μg/mL; Diuron; Propham; Siduron; Methiocarb, analytical standard; Linuron 10 μg/mL; Swep 10 μg/mL; Chlorpropham 10 μg/mL; Barban; Neburon
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