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Merck

WH0004041M1

Sigma-Aldrich

Monoclonal Anti-LRP5 antibody produced in mouse

clone 1E9, purified immunoglobulin, buffered aqueous solution

别名:

Anti-BMND1, Anti-HBM, Anti-LR3, Anti-LRP7, Anti-OPPG, Anti-OPS, Anti-VBCH2, Anti-low density lipoprotein receptor-related protein 5

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1E9, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG1κ

GenBank登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LRP5(4041)

一般說明

Low-density lipoprotein receptor-related protein 5 or LRP5 functions as a co-receptor for the Wnt signaling complex. LRP5 is involved in various processes such as bone mass regulation, pulmonary angiogenesis, and alveolar synthesis . Monoclonal Anti-LRP5 antibody is specific for LRP5 in humans.

免疫原

LRP5 (NP_002326.1, 41 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Tadanori Mammoto et al.
PloS one, 7(7), e41596-e41596 (2012-08-01)
Angiogenesis is crucial for lung development. Although there has been considerable exploration, the mechanism by which lung vascular and alveolar formation is controlled is still not completely understood. Here we show that low-density lipoprotein receptor-related protein 5 (LRP5), a component
Yajun Cui et al.
Nature medicine, 17(6), 684-691 (2011-05-24)
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5). To understand how LRP5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5 mutations that cause high and low bone mass phenotypes in

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