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Merck

V0131

Sigma-Aldrich

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat

≥97% (HPLC)

别名:

VIP 1-12

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About This Item

经验公式(希尔记法):
C61H88N18O22
分子量:
1425.46
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26

产品名称

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat, ≥97% (HPLC)

质量水平

方案

≥97% (HPLC)

表单

solid

UniProt登记号

应用

cell analysis

储存温度

−20°C

SMILES字符串

CC(C)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C61H88N18O22/c1-27(2)46(77-49(89)28(3)69-51(91)40(22-44(85)86)73-56(96)42(25-80)76-50(90)35(62)20-33-24-66-26-68-33)57(97)74-38(18-31-10-7-6-8-11-31)55(95)79-48(30(5)82)59(99)75-41(23-45(87)88)53(93)72-39(21-43(63)84)52(92)71-37(19-32-13-15-34(83)16-14-32)54(94)78-47(29(4)81)58(98)70-36(60(100)101)12-9-17-67-61(64)65/h6-8,10-11,13-16,24,26-30,35-42,46-48,80-83H,9,12,17-23,25,62H2,1-5H3,(H2,63,84)(H,66,68)(H,69,91)(H,70,98)(H,71,92)(H,72,93)(H,73,96)(H,74,97)(H,75,99)(H,76,90)(H,77,89)(H,78,94)(H,79,95)(H,85,86)(H,87,88)(H,100,101)(H4,64,65,67)

InChI key

OZQVVUDUPMJWPH-UHFFFAOYSA-N

基因信息

human ... VIP(7432)

Amino Acid Sequence

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg

生化/生理作用

Ligand for CD4 receptor.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K J Sung et al.
Neuropeptides, 33(6), 435-446 (2000-02-05)
It is well known that psoriasis, an immunogenetic cutaneous disorder whose major pathogenic findings are epidermal hyperplasia and T-cell infiltration, is aggravated by psychological stresses. Although the exact mechanism is not yet clarified, antidromic secretion of neuropeptides by cutaneous nerve
M Ichinose et al.
Regulatory peptides, 54(2-3), 457-466 (1994-12-15)
The effect of VIP on phagocytosis in peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that VIP suppressed phagocytosis in a dose-dependent manner. VIP(1-12) did not suppress phagocytosis. VIP(10-28) was more suppressive than VIP(1-28). A
F Séjourné et al.
The American journal of physiology, 273(1 Pt 2), R287-R292 (1997-07-01)
The purpose of this study was to begin to determine the mechanisms underlying vasodilation elicited by vasoactive intestinal peptide (VIP) in sterically stabilized liposomes (SSL) in the in situ peripheral microcirculation. Using intravital microscopy, we found that suffusion of VIP
S Chakder et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 392-399 (1993-07-01)
Because no significant information exists regarding the structure-activity of vasoactive intestinal polypeptide (VIP) to gut smooth muscle, we performed functional studies in vitro on opossum internal anal sphincter (IAS) smooth muscle strips and supplemented them with binding studies to assess
P Sacerdote et al.
Journal of neuroscience research, 18(1), 102-107 (1987-01-01)
A five-amino-acid (TDNYT) sequence of vasoactive intestinal polypeptide (VIP) shares homology with the proposed attachment sequences of the human immunodeficiency virus (HIV). Synthetic peptides with these sequences have previously been shown to block viral envelope (gp120) binding and HIV infectivity

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