推荐产品
化驗
≥97% (HPLC)
藥物控制
regulated under CDSA - not available from Sigma-Aldrich Canada
顏色
white to off-white
mp
≥205 °C
溶解度
acetonitrile: soluble
ethanol: soluble
methanol: soluble
儲存溫度
2-8°C
SMILES 字串
C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
InChI
1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1
InChI 密鑰
XSEGWEUVSZRCBC-ZVBLRVHNSA-N
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應用
6β-Hydroxytestosterone has been used for CYP3A activity assays in rat hepatocytes and has also been used for CYP3A4 substrate selection studies.
生化／生理作用
6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic.
準備報告
6β-Hydroxytestosterone is soluble in methanol, acetonitrile and ethanol.
取代透過
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Carc. 2 - Repr. 1B
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Aleksandra Galetin et al.
The Journal of pharmacology and experimental therapeutics, 314(1), 180-190 (2005-03-24)
The complexity of in vitro kinetic phenomena observed for CYP3A4 substrates (homo- or heterotropic cooperativity) confounds the prediction of drug-drug interactions, and an evaluation of alternative and/or pragmatic approaches and substrates is needed. The current study focused on the utility
Yoshitaka Miyamoto et al.
Cell transplantation, 18(5), 677-681 (2009-09-25)
Three-dimensional culture procedures have attracted attention in various fields of cell biology. A newly developed cell array assisted in the formation of hepatocyte spheroids by two innovations: 1) micropatterning by a hydrophilic polymer, and 2) the use of bovine carotid
Zhen Lou et al.
The Journal of steroid biochemistry and molecular biology, 82(4-5), 413-424 (2003-02-19)
Intestinal or hepatic microsomes from channel catfish converted [4-14C]-testosterone to three major metabolites: 6 beta-hydroxytestosterone, androstenedione and a third metabolite. Formation of the unknown metabolite required NADPH as cofactor. When incubated with 200 microM testosterone, the rate of formation of
Yong Liu et al.
Biological & pharmaceutical bulletin, 27(10), 1555-1560 (2004-10-07)
The intestinal bacterial metabolites of ginsenosides are responsible for the main pharmacological activities of ginseng. The purpose of this study was to find whether these metabolites influence hepatic metabolic enzymes and to predict the potential for ginseng-prescription drug interactions. Utilizing
Cuiping Chen et al.
The Journal of pharmacology and experimental therapeutics, 300(2), 417-420 (2002-01-24)
The adrenochrome reaction (oxidation of epinephrine to adrenochrome) has been widely employed as a standard assay for reactive oxygen species, produced under a variety of conditions, including those produced during cytochrome P450 (CYP)-mediated oxidation of substrates such as cyclosporine. However
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