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化驗
≥98% (HPLC)
顏色
light brown to brown
溶解度
DMSO: >10 mg/mL
儲存溫度
2-8°C
SMILES 字串
O.Oc1ccc2C(=O)c3ccc(O)c(O)c3Oc2c1O
InChI
1S/C13H8O6.H2O/c14-7-3-1-5-9(16)6-2-4-8(15)11(18)13(6)19-12(5)10(7)17;/h1-4,14-15,17-18H;1H2
InChI 密鑰
ZFTTXYRPFMYDRT-UHFFFAOYSA-N
生化／生理作用
3,4,5,6-Tetrahydroxyxanthone is a Na/K-ATPase inihibitor that inhibits pump function without activating the kinase signaling function. It inhibits Na/K ATPase pump action with an affinity comparable to ouabain, but does not alter Na or ATP affinity, is not blocked by potassium, and it does not activate the Src complex or downstream kinases.
準備報告
3,4,5,6-Tetrahydroxyxanthone hydrate is soluble in DMSO at a concentration that is greater than 10 mg/ml.
訊號詞
Danger
危險聲明
防範說明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Orhan Aktas et al.
The Journal of experimental medicine, 197(6), 725-733 (2003-03-12)
Statins, known as inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, exhibit numerous functions related to inflammation, such as MHC class II down-regulation, interference with T cell adhesion, and induction of apoptosis. Here we demonstrate that both subcutaneous and oral administration
Rodrigo Quezada et al.
Nanomaterials (Basel, Switzerland), 10(6) (2020-06-12)
Type of metal and metal-oxide NPs added to modify Thin-Film Composites Reverse Osmosis Membranes (TFC-RO) can alter their anti-biofouling properties by changing the dissolution process. The development of a mathematical model can facilitate the selection of these NPs. This work
M Armendariz Ontiveros et al.
Materials (Basel, Switzerland), 12(13) (2019-07-03)
The anti-biofouling and desalination properties of thin film composite reverse osmosis membranes (TFC-RO), modified by the incorporation of copper and iron nanoparticles, were compared. Nanoparticles of metallic copper (CuNPs) and an iron crystalline phase mix (Fe and Fe2O3, FeNPs) were
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