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描述
non-ionic
產品線
BioXtra
形狀
liquid (clear)
雜質
<0.5% water (Coulometric)
<5 ppm heavy metal
顏色
colorless to light yellow
mp
≤ -100 °C
溶解度
water: soluble 3420 g/L
密度
1.09 g/mL at 25 °C (lit.)
InChI
1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
InChI 密鑰
CTPDSKVQLSDPLC-UHFFFAOYSA-N
應用
四甘醇 已用于：
- 稀释Dil（1,1′-二十八烷基-3,3,3′3′-四甲基吲哚菁高氯酸盐）以注入受精卵进行Dil标记
- 稀释Dil（1,1′-二十八烷基-3,3,3′3′-四甲基吲哚菁高氯酸盐）和diO（3,3′-二十八烷基氧杂碳菁高氯酸盐）以进行染料/病毒注射
- 稀释聚（丙交酯-co-乙交酯）（PLGA）以制备PLGA/F127溶液
用作溶剂以溶解水不溶性化合物。
生化／生理作用
液体糖原质因其具有很好的弹性，可轻松转化为凝胶体系，用作溶于水不溶性药物的介质。
特點和優勢
格列本脲（GBD）的高效增溶剂
注意
请勿与三缩四乙二醇混淆，其有时也称为四甘醇。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
275.0 °F - closed cup
閃點（°C）
135 °C - closed cup
個人防護裝備
Eyeshields, Gloves
其他客户在看
Saly Galal et al.
Acta pharmaceutica (Zagreb, Croatia), 53(1), 57-64 (2004-02-11)
The ability of liquid and semi-solid matrix (SSM) filling capsule technology to improve the dissolution rate of glibenclamide (GBD) was investigated. Semiquantitative estimation of GBD solubility in various vehicles was carried out. Tetraglycol was found to be the most efficient
X F Zhang et al.
Materials science & engineering. C, Materials for biological applications, 32(6), 1654-1663 (2012-08-01)
Poly (lactide-co-glycolide) (PLGA) - Pluronic F127 - glass composites have demonstrated excellent potential, from the perspective of controlled mechanical properties and cytocompatibility, for peripheral nerve regeneration. In addition to controlling the mechanical properties and cytotoxicity for such composite devices, the
Nahla Salah Barakat
AAPS PharmSciTech, 11(3), 1138-1146 (2010-07-24)
In view of the good skin tolerability, glycofurol was used as a vehicle-based gel, and its effect in the topical penetration of Naproxen (NAP) was investigated. The aims of this study were to develop a suitable gel with bioadhesive property
S Kehoe et al.
Journal of the mechanical behavior of biomedical materials, 14, 180-185 (2012-10-03)
PLGA/pluronic F127 based nerve guidance conduits (NGCs) for peripheral nerve regeneration offer excellent potential for clinical use. To date, little emphasis has been directed towards the effect of pluronic F127 on their subsequent mechanical properties as a function of degradation
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