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Merck

T2402

Sigma-Aldrich

抗- 小鼠IgG(全分子)−TRITC 兔抗

IgG fraction of antiserum, buffered aqueous solution

别名:

Rabbit Anti-Mouse IgG (whole molecule)−Tetramethylrhodamine isothiocyanate

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

共軛

TRITC conjugate

抗體表格

IgG fraction of antiserum

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

儲存條件

protect from light

技術

direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

免疫球蛋白(Ig)属于免疫球蛋白超家族。存在有五种不同类型的免疫球蛋白。每种免疫球蛋白包含有两条重链(H)和两条轻链(L),它们通过二硫键连接。每条轻链包含一个可变的N-端区域和一个恒定C-端区域。重链包含有一个可变的N-端区域以及三个或四个恒定的(CH1-CH4)C-末端区域。IgG是在人血清中丰度较高的免疫球蛋白。IgG 的四种类型分别为IgG1、IgG2、IgG3和IgG4。

特異性

抗-小鼠IgG(全分子)-TRITC抗体对小鼠IgG具有特异性。

免疫原

正常小鼠血清

應用

抗小鼠IgG(全分子)-TRITC抗体适用于直接免疫荧光(1:64)、免疫组化(福尔马林固定、石蜡包埋切片1:200稀释)、Ouchterlony双扩散和电泳技术。

生化/生理作用

免疫球蛋白G(IgG)是一种糖蛋白抗体,可调节免疫反应(如吞噬作用),也可影响自身免疫疾病的进程。小鼠IgG具有四种不同的亚型,即IgG1、IgG2a、IgG2b和IgG3。IgG1可调节小鼠的补体结合。
木瓜蛋白酶对IgG的消化导致产生片段抗原结合(Fab),该片段包含一个完整的L链和H链的可变区和CH1区。IgG的胃蛋白酶消化产生可结晶片段(fc),包含H链恒定区。

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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