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Merck

T0699

Sigma-Aldrich

三氯乙酸 溶液

6.1 N

别名:

TCA

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About This Item

线性分子式:
Cl3CCOOH
CAS号:
分子量:
163.39
Beilstein:
970119
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.26

表单

liquid

浓度

6.1 N
~100 % (w/v)

SMILES字符串

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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一般描述

三氯乙酸(TCA)是一种强酸。在饮用水pH值下,三氯乙酸呈现盐形式。

应用

三氯乙酸的应用示例:
  • 用于吲哚胺2,3-双加氧酶(IDO)活性测定,水解N-甲酰犬尿氨酸并生成犬尿氨酸
  • 用于人肺动脉平滑肌细胞(HPASMCs)增殖
  • 在蛋白提取和定量时,处理研磨组织和沉淀蛋白

生化/生理作用

三氯乙酸(TCA)全身性无毒,长久以来被用作浅表脱皮试剂。可用作过氧化物酶体增殖剂。
三氯乙酸溶液一般用于沉淀蛋白。可用于通过定量沉淀法测定蛋白浓度。三氯乙酸也可用作显微脱钙剂和固定剂。

警示用语:

Danger

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

靶器官

Respiratory system

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guillaume Laflamme et al.
Cell reports, 26(11), 2875-2889 (2019-03-14)
The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or
Hikmat Al-Ahmadie et al.
Cancer discovery, 4(9), 1014-1021 (2014-06-18)
Metastatic solid tumors are almost invariably fatal. Patients with disseminated small-cell cancers have a particularly unfavorable prognosis, with most succumbing to their disease within two years. Here, we report on the genetic and functional analysis of an outlier curative response
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
Ying Wang et al.
Diabetes, 63(8), 2643-2655 (2014-03-13)
After diabetes, the heart has a singular reliance on fatty acid (FA) for energy production, which is achieved by increased coronary lipoprotein lipase (LPL) that breaks down circulating triglycerides. Coronary LPL originates from cardiomyocytes, and to translocate to the vascular
Inga Müller et al.
PloS one, 9(5), e97285-e97285 (2014-05-27)
Members of the MYC family are the most frequently deregulated oncogenes in human cancer and are often correlated with aggressive disease and/or poorly differentiated tumors. Since patients with MYCN-amplified neuroblastoma have a poor prognosis, targeting MYCN using small molecule inhibitors

实验方案

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

This procedure may be used for determination of Pepsin activity using hemoglobin as the substrate. It is a spectrophotometric stop rate determination.

本方法可用于以血红蛋白为底物的胃蛋白酶活性测定。这是一种分光光度速率终止测定法。

本操作程序可用于使用淀粉作为底物测定淀粉葡萄糖苷酶的活性。

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