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Merck
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文件

T0656

Sigma-Aldrich

1,3,4,6-四氯-3α,6α-二苯基甘脲

别名:

Iodo-Gen®, NSC 4462

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About This Item

经验公式（希尔记法）:
C16H10Cl4N4O2
CAS号:
51592-06-4
分子量:
432.09
MDL號碼:
MFCD00027367
分類程式碼代碼:
12352101
PubChem物質ID:
24899904
NACRES:
NA.22

儲存溫度

2-8°C

品質等級

100

SMILES 字串

ClN1C(=O)N(Cl)C2(N(Cl)C(=O)N(Cl)C12c3ccccc3)c4ccccc4

InChI

1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H

InChI 密鑰

FJQZXCPWAGYPSD-UHFFFAOYSA-N

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相关类别

應用

用作氧化剂的放射性碘化用碘化试剂

用于氯胺-T 比较研究的试剂

用于氧化咪唑的试剂

法律資訊

Iodo-Gen is a registered trademark of Pierce Biotechnology, Inc.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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G W Visser et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 42(3), 509-519 (2001-05-05)
A novel, facile procedure for efficient coupling of high doses of (131)I to monoclonal antibodies (MAbs) was developed with minimal chemical and radiation damage. To diminish the radiation and chemical burden during labeling, iodination was performed in a large reaction
E Carnazzi et al.
Journal of medicinal chemistry, 37(12), 1841-1849 (1994-06-10)
A series of new linear photoactivatable and iodinatable antagonists of the neuropeptidic hormone vasopressin was designed and synthesized by a combination of PyBOP-mediated Boc/solid-phase peptide synthesis and solution synthesis approaches. These were based on modifications of a previously reported potent
Helge Wiig et al.
The Journal of physiology, 567(Pt 2), 557-567 (2005-07-05)
Knowledge of macromolecular distribution volumes is essential in understanding fluid transport within normal and pathological tissues. In this study in vivo we determined the distribution volumes of several macromolecules, including one monoclonal antibody, in tumours and tested whether charges associated
P K Garg et al.
Bioconjugate chemistry, 7(2), 233-239 (1996-03-01)
Two peptides of potential utility for targeting melanoma cells, alpha-melanocyte-stimulating hormone (alpha-MSH) and its more potent analogue [Nle4,D-Phe7]-alpha-MSH, were radioiodinated in 45-65% yield using N-succinimidyl 3-[125I]iodobenzoate (SIB). To determine whether this labeling method resulted in improved in vitro and in
P K Garg et al.
Bioconjugate chemistry, 6(4), 493-501 (1995-07-01)
The F(ab')2 fragment of monoclonal antibody (MAb) Me1-14 was labeled with 125I using the Iodogen method and by reaction with N-succinimidyl 3-[125I]iodobenzoate (SIB). The labeled catabolites generated after exposure to tissue homogenates in vitro and following administration of labeled F(ab')2
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