SRP5265

HDAC1, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 别名: DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
• UNSPSC代码: 12352202
• NACRES: NA.32

属性

• 重组: expressed in baculovirus infected Sf9 cells
• 方案: ≥70% (SDS-PAGE)
• 表单: buffered aqueous glycerol solution
• 比活: 7565-11765 RLU/min·ng
• 分子量: ~88 kDa
• NCBI登记号: NM_004964
• 运输: dry ice
• 储存温度: −70°C
• 基因信息: human ... HDAC1(3065)

说明

一般描述

HDAC1 or Histone deacetylase 1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex which plays a key role in the regulation of eukaryotic gene expression. HDAC1 interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is an essential element of the co-activation system for IFN-induced gene regulation and antiviral responses.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable