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生物源
human
重組細胞
expressed in E. coli
化驗
≥90% (SDS-PAGE)
形狀
aqueous solution
分子量
16.2 kDa
包裝
pkg of 100 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... ATAD2(29028)
一般說明
Human Bromodomain ATAD2A (GenBank Accession No. NM_014109) amino acids 981 – 1108 with N-terminal HIS-tag, MW = 16.2 kDa, expressed in an E. coli expression system.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
C Caron et al.
Oncogene, 29(37), 5171-5181 (2010-06-29)
Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly expressed in testis as
Ekaterina V Kalashnikova et al.
Cancer research, 70(22), 9402-9412 (2010-09-25)
Chromatin coregulators are important factors in tumorigenesis and cancer progression. ANCCA is an AAA+ ATPase and a bromodomain-containing nuclear coactivator for the estrogen and androgen receptors that is crucial for assembly of chromatin-modifying complexes and proliferation of hormone-responsive cancer cells.
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