推荐产品
质量水平
方案
≥98% (HPLC)
表单
oil
颜色
off-white to brown
储存温度
2-8°C
SMILES字符串
CC1=CC=CC(S(N(C)[C@H](C)CCN2CCC(C)CC2)(=O)=O)=C1
InChI
1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3
InChI key
AGVNHDNTFYHZNL-UHFFFAOYSA-N
生化/生理作用
SB-258719 是一种选择性和有效的 5-HT7 拮抗剂。SB-258719 逆转了 5-CT 对小鼠的低温作用。
选择性和有效的 5-HT7 拮抗剂
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Xin Zhao et al.
Scientific reports, 5, 9043-9043 (2015-03-13)
Fisetin, a natural flavonoid, has been shown in our previous studies to exert antidepressant-like effect. As antidepressant drugs are clinically used to treat chronic neuropathic pain, this work aimed to investigate the potential antinociceptive efficacies of fisetin against neuropathic pain
D R Thomas et al.
British journal of pharmacology, 124(6), 1300-1306 (1998-08-28)
1. The functional profile of the long form of the human cloned 5-HT7 receptor (designated h5-HT7(a)) was investigated using a number of 5-HT receptor agonists and antagonists and compared with its binding profile. Receptor function was measured using adenylyl cyclase
Sarwat Fatima et al.
Molecular oncology, 10(2), 195-212 (2015-10-18)
5-Hydroxytryptamine (5-HT), a neurotransmitter and vasoactive factor, has been reported to promote proliferation of serum-deprived hepatocellular carcinoma (HCC) cells but the detailed intracellular mechanism is unknown. As Wnt/β-catenin signalling is highly dysregulated in a majority of HCC, this study explored
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