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生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 55 kDa
物種活性
human, mouse, rat
濃度
~1 mg/mL
技術
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pSer473)
基因資訊
human ... AKT1(207)
rat ... Akt1(24185)
一般說明
AKT1 (AKT 丝氨酸/苏氨酸激酶1也称 v-akt 鼠胸腺瘤病毒致癌基因同系物1 和PKBα (蛋白激酶B)。它在肝脏、肌肉和脂肪细胞中表达。AKT1 基因位于人类染色体14q32上。它是AKT家族成员,具有氨基末端普列克底物蛋白同源 (pleckstrin homology,PH)结构域、短链α-螺旋连接子和羧基末端激酶结构域。
免疫原
在 Ser473 的磷酸化站点附近产生抗血清对抗来自人 Akt 的合成肽。
免疫原范围: 431-480
免疫原范围: 431-480
生化/生理作用
AKT1(AKT丝氨酸/苏氨酸激酶1)控制细胞的存活和攻击发病机制的抗凋亡作用几种癌症,因此,它在肿瘤发生中起角色至关重要的作用。在小鼠中,AKT1对正常发育至关重要。
特點和優勢
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多。
外觀
兔 IgG 溶于磷酸盐缓冲盐水(不含 Mg2+ 和 Ca2+),pH7.4,150mM NaCl,0.02% 叠氮化钠和 50% 甘油中。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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