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Merck

SAB4502676

Sigma-Aldrich

Anti-S6 Ribosomal Protein, C-Terminal antibody produced in rabbit

affinity isolated antibody

别名:

40S ribosomal protein S6, Phosphoprotein NP33, RPS6, RS6, ribosomal protein S6

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 28 kDa

物種活性

rat, mouse, human

濃度

~1 mg/mL

技術

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... RPS6(6194)

一般說明

Anti-S6 Ribosomal protein antibody detects endogenous levels of total S6 Ribosomal protein protein.
The RPS6 (ribosomal protein S6) gene is mapped to human chromosome 9p22.1.

免疫原

The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein.

Immunogen Range: 191-240

生化/生理作用

The RPS6 (ribosomal protein S6) protein is involved in the 40S subunit assembling. RpS6 might be involved in the regulation of cellular metabolism, the size of cells, their proliferation and survival. RpS6 might stimulate or inhibit translation of certain mRNA. Upregulation of the gene is observed in pulmonary sclerosing hemangioma, lymphangioleiomyomatosis-associated angiomyolipomas, dysplasia, oral cavity and esophageal squamous cell carcinoma.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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访问文档库

Janice Chithelen et al.
Frontiers in physiology, 13, 856143-856143 (2022-04-05)
The bioactive sphingolipids ceramide and sphingosine-1-phosphate (S1P) are involved in the regulation of cell homeostasis and activity ranging from apoptosis to proliferation. We recently described that the two compounds ceranib-2 (inhibiting acid ceramidase) and SKI-II [inhibiting the sphingosine kinases 1
Aggregation of Ribosomal Protein S6 at Nucleolus Is Cell Cycle-Controlled and Its Function in Pre-rRNA Processing Is Phosphorylation Dependent.
Zhang D
Journal of Cellular Biochemistry, 117(7), 1649-1657 (2016)
Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer.
Chen B
Journal of Experimental & Clinical Cancer Research, 34:126, 1-16 (2015)
Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway.
Presneau N
British Journal of Cancer, 100(9), 1406-1414 (2009)

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