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生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 36 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... ADORA2B(136)
一般說明
Anti-ADORA2B Antibody detects endogenous levels of total ADORA2B protein.
ADORA2B (adenosine A2b receptor) is a G-protein coupled receptor. It is the most adenosine insensitive adenosine receptor. This gene is located on human chromosome 17p12-p11.2. Anti-ADORA2B Antibody detects endogenous levels of total ADORA2B protein.
ADORA2B (adenosine A2b receptor) is a G-protein coupled receptor. It is the most adenosine insensitive adenosine receptor. This gene is located on human chromosome 17p12-p11.2. Anti-ADORA2B Antibody detects endogenous levels of total ADORA2B protein.
免疫原
The antiserum was produced against synthesized peptide derived from human ADORA2B.
Immunogen Range: 231-280
Immunogen Range: 231-280
生化／生理作用
ADORA2B (adenosine A2b receptor) acts as a therapeutic target for cancer treatment. The tumor cells can use A2b receptor to induce tumor progression. ADORA2B controls immune cell activity. It plays a major role in the transcriptional induction and protein stability of protein period 2 (Per2).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.
Eckle T, et al.
Nature Medicine, 18(5), 774-774 (2012)
CD73-Dependent Generation of Adenosine and Endothelial Adora2b Signaling Attenuate Diabetic Nephropathy.
Eunyoung T, et al.
Journal of the American Society of Nephrology, 25 (3), 547-563 (2014)
Role of adenosine A2b receptor overexpression in tumor progression.
Sepulveda C, et al.
Life Sciences, 166, 92-99 (2016)
Pharmacogenetics of asthma.
Fenech A and Hall IP
British Journal of Clinical Pharmacology, 53(1), 3-15 (2002)
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism.
M?lck C, et al.
Cancer Letters, 383(1), 135-143 (2016)
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