SAB4500110

Anti-C/EBP-α antibody produced in rabbit

affinity isolated antibody

• 别名: C/EBP α, CCAAT/enhancer binding protein α, CCAAT/enhancer binding protein (C/EBP) α, CEBPA
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 37 kDa
• 物種活性: mouse, rat, human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: P49715
• UniProt登錄號: P49715
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CEBPA(1050)

说明

一般說明

Anti-C/EBP-α Antibody detects endogenous levels of total C/EBP-α protein.

CCAAT/enhancer-binding protein α (C/EBPα) is encoded by the gene mapped to human chromosome 19q13.1. The encoded protein belongs to the basic leucine zipper (bZIP) family of transcription factors. CEBPA is highly expressed in differentiated tissues.

免疫原

The antiserum was produced against synthesized peptide derived from human C/EBP-alpha.

Immunogen Range: 6-55

生化／生理作用

The transcription factor CCAAT/enhancer-binding protein α (C/EBPα) plays an essential role in tumor progression. It blocks β-catenin to repress lung adenocarcinoma cell invasion and migration. CEBPA is implicated in the regulation of hematopoiesis and terminal differentiation of various cell types like adipocytes, hepatocytes and different epithelial cells. Variations in the gene expression has been observed in 5–10% of cases of acute myeloid leukemia (AML).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable