推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
55-60 kDa
种属反应性
mouse, rat, human
浓度
1 mg/mL
技术
indirect immunofluorescence: 1:100-1:200
同位素/亚型
IgG
免疫原序列
(R-Q-SP-L-I)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pSer40)
基因信息
human ... TH(7054)
免疫原
Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I), according to the protein TH.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
目标描述
The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Kyoung In Kim et al.
Experimental neurobiology, 28(2), 289-299 (2019-05-30)
Transient receptor potential vanilloid subtype 1 (TRPV1) on astrocytes prevents ongoing degeneration of nigrostriatal dopamine (DA) neurons in MPP+-lesioned rats via ciliary neurotrophic factor (CNTF). The present study determined whether such a beneficial effect of astrocytic TRPV1 could be achieved
Bárbara Rangel da Silva et al.
Cellular and molecular neurobiology, 39(1), 99-109 (2018-11-16)
Neurospheres prepared from multipotent progenitors in the retina obtained from postnatal mice differentiate into neurons and Müller glia (De Melo Reis et al., in Cell Mol Neurobiol 31:835-846, 2011). Here, we investigated whether neurospheres prepared from adult chickens (ciliary marginal
Rosilane Taveira-da-Silva et al.
Kidney & blood pressure research, 44(1), 1-11 (2019-02-28)
Dopamine (DA) is a natriuretic hormone that inhibits renal sodium reabsorption, being Angiotensin II (Ang II) its powerful counterpart. These two systems work together to maintain sodium homeostasis and consequently, the blood pressure (BP) within normal limits. We hypothesized that
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