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Merck

SAB2500444

Sigma-Aldrich

Anti-GAD2/GAD65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-GAD65, Anti-Glutamate decarboxylase 2

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, mouse, chimpanzee, rat, canine

技術

indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GAD2(2572)

一般說明

Glutamate decarboxylase 2 (GAD2) is a 65kDa protein expressed in β-cells. The gene encoding this protein is localized on human chromosome 10p12.1.

免疫原

Peptide with sequence C-TLEDNEERMSRLSK from the internal region of the protein sequence according to NP_000809.1.

生化/生理作用

Glutamate decarboxylase 2 (GAD2) is an isoform of glutamate decarboxylase, which is involved in the synthesis of γ-aminobutyric acid (GABA). GAD2 is an auto-antigen in type I diabetes and has been shown to have a role in gastric cancer.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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在文件库中查找您最近购买产品的文档。

访问文档库

Plasma GAD65, a Marker for Early ?-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.
Ling Z
The Journal of Clinical Endocrinology and Metabolism (2015)
Immuno-chemistry of hydroxyl radical modified GAD-65: A possible role in experimental and human diabetes mellitus.
Moinuddin
IUBMB Life, 67(10) (2015)
The role of glutamate decarboxylase 65 in gastric cancer development, progression, and prognosis.
Song Y
Histopathology (2013)
Epigenetic signature of panic disorder: A role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?
Katharina D
Progress in Neuro-Psychopharmacology & Biological Psychiatry (2013)

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