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生物源
goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, mouse, chimpanzee, rat, canine
技術
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GAD2(2572)
一般說明
Glutamate decarboxylase 2 (GAD2) is a 65kDa protein expressed in β-cells. The gene encoding this protein is localized on human chromosome 10p12.1.
免疫原
Peptide with sequence C-TLEDNEERMSRLSK from the internal region of the protein sequence according to NP_000809.1.
生化/生理作用
Glutamate decarboxylase 2 (GAD2) is an isoform of glutamate decarboxylase, which is involved in the synthesis of γ-aminobutyric acid (GABA). GAD2 is an auto-antigen in type I diabetes and has been shown to have a role in gastric cancer.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Plasma GAD65, a Marker for Early ?-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.
The Journal of Clinical Endocrinology and Metabolism (2015)
Immuno-chemistry of hydroxyl radical modified GAD-65: A possible role in experimental and human diabetes mellitus.
IUBMB Life, 67(10) (2015)
The role of glutamate decarboxylase 65 in gastric cancer development, progression, and prognosis.
Histopathology (2013)
Epigenetic signature of panic disorder: A role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?
Progress in Neuro-Psychopharmacology & Biological Psychiatry (2013)
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