SAB1300893

Anti-TYRO10 antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

• 别名: Anti-Discoidin domain receptor 2, Anti-Neurotrophic tyrosine kinase, Anti-Receptor protein-tyrosine kinase TKT, Anti-Tyrosine-protein kinase TYRO 10, receptor-related 3
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: saturated ammonium sulfate (SAS) precipitated
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 种属反应性: human
• 技术: indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI登记号: NP_006173
• UniProt登记号: Q16832
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... TYRO10(4921)

说明

一般描述

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.

免疫原

TYRO10 ()
This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable