所有图片(4)
About This Item
线性分子式:
C13H21NO3 · 1/2H2SO4
CAS号:
分子量:
288.35
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
≥98%
溶解度
1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green
起源
GlaxoSmithKline
SMILES 字串
OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2
InChI
1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
InChI 密鑰
BNPSSFBOAGDEEL-UHFFFAOYSA-N
基因資訊
human ... ADRB2(154)
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應用
Salbutamol hemisulfate salt has been used as reference standards of drugs for the validation of β-agonist residue.
Salbutamol hemisulfate salt was used as standard in analysis of fortified meat for LABA content using ELISA kits.3 It was used to study the response of prostaglandin 2α to various β-adrenergic agonists in cultured bovine endometrial cells.4
生化／生理作用
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP). Salbutamol is particularly effective in treatment of asthma as it provides immediate relief. Salbutamol is one of the most popular short-acting BA (SABA). It is useful in treating the symptoms of EIB (exercise induced bronchospasm).
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2
β2-Adrenergic receptor agonist.
特點和優勢
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險聲明
危險分類
Carc. 2 - Repr. 2 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
R S Pirie et al.
Journal of veterinary pharmacology and therapeutics, 40(3), 231-238 (2016-09-07)
Despite frequent use of metered dose inhalers (MDIs) and spacers in equine practice, limited information exists on the efficiency of aerosol delivery using such devices. We determined the particle size distribution within an MDI-generated salbutamol aerosol delivered via an equine
Medical and pharmacological approach to adjust the salbutamol anti-doping policy in athletes
Pillard F, et al.
Respiratory Research, 16(1), 155-155 (2015)
Validation of ELISA test kits for detection of beta-agonist residues in meat
Ponniah J, et al.
The Southeast Asian Journal of Tropical Medicine and Public Health, 35(1), 481-487 (2004)
B Padhukasahasram et al.
The pharmacogenomics journal, 14(4), 365-371 (2014-01-15)
Inhaled short-acting beta-agonist (SABA) medication is commonly used in asthma patients to rapidly reverse airway obstruction and improve acute symptoms. We performed a genome-wide association study of SABA medication response using gene-based association tests. A linear mixed model approach was
R K Dutta et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 142, 112090-112090 (2021-09-01)
MicroRNAs play an important role in health and disease. TGF-β signaling, upregulated by HIV Tat, and in chronic airway diseases and smokers upregulates miR-145-5p to suppress cystic fibrosis transmembrane conductance regulator (CFTR). CFTR suppression in chronic airway diseases like Cystic
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