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Merck

RAB1475

Sigma-Aldrich

人半乳凝素9 ELISA

for serum, plasma and cell culture supernatants

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

human

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable

輸入

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 36 pg/mL
standard curve range: 36.86-9000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... LGALS9(3965)

一般說明

Galectin-9 is generally a part of extracellular secretions but is also localized to endothelial cells, T cells and dendritic cells. Galectin-9 is a S-type lectin and its gene is mapped to human chromosome 17q11.2.
This ELISA antibody pair detects Human Galectin-9 (LGALS9)

應用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

Galectin is a β-galactoside-binding secretory protein, which also has a carbohydrate-recognition domain. Galectin contributes to cancer progression by interacting with oncogenic proteins on the cell surface, such as integrins, fibronectin and laminin. Galectin is also known to suppress immune response in conditions such as melanoma, neuroblastoma and pancreatic carcinoma.

其他說明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Elevated Galectin-9 Suppresses Th1 Effector Function and Induces Apoptosis of Activated CD4+ T Cells in Osteoarthritis.
Yang S, et al.
Inflammation, 40(3), 1062-1071 (2017)
Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway.
Luo L H, et al.
Biochemical and Biophysical Research Communications, 491(4), 966-972 (2017)
Characterization of a de novo sSMC 17 detected in a girl with developmental delay and dysmorphic features.
Stavber L, et al.
Molecular Cytogenetics, 10(1), 10-10 (2017)
Galectin-9 binds to O-glycans on protein disulfide isomerase.
Schaefer K, et al.
Glycobiology, 27(9), 878-887 (2017)
Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells.
KeeSoo N, et al.
Oncotarget, 8(22), 35804-35823 (2017)

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