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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/mL
standard curve range: 0.96-700 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... DCN(1634)
一般說明
Decorin comprises dermatan sulfate or a chondroitin sulfate chain. It belongs to the small leucine-rich proteoglycan (SLRP) gene family and is expressed majorly in the myofibroblasts and fibroblasts.
The Human Decorin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Decorin in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human Decorin
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Decorin ELISA Kit has been used in sandwich enzyme-linked immunosorbent assay (ELISA) of mice serum. It has also been used in the ELISA of plasma samples and cerebrospinal fluid (CSF) of glioma patients.
生化／生理作用
Decorin is involved in a wide variety of biological processes including cell differentiation, growth and muscle development. It also takes part in wound healing, angiogenesis and regulates autophagy and inflammation. Decorin interacts with matrix proteins and inhibits tumor migration and growth.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
Mohammad F Siddiqui et al.
American journal of obstetrics and gynecology, 215(3), 361-361 (2016-03-24)
Decorin, a leucine-rich proteoglycan that is produced by decidual cells, limits invasion and endovascular differentiation of extravillous trophoblast cells during early placentation by binding to multiple tyrosine kinase receptors, in particular, vascular endothelial growth factor receptor-2. Because many studies have
Andrea Reszegi et al.
Frontiers in oncology, 10, 645-645 (2020-06-02)
Hepatocellular carcinoma (HCC) represents one of the most frequent type of primary liver cancers. Decorin, a small leucine-rich proteoglycan of the extracellular matrix, represents a powerful tumor cell growth and migration inhibitor by hindering receptor tyrosine kinases and inducing p21WAF1/CIP1.
Dong-Ming Kuang et al.
The Journal of clinical investigation, 124(10), 4657-4667 (2014-09-23)
Classical IL-22-producing T helper cells (Th22 cells) mediate inflammatory responses independently of IFN-γ and IL-17; however, nonclassical Th22 cells have been recently identified and coexpress IFN-γ and/or IL-17 along with IL-22. Little is known about how classical and nonclassical Th22
Andrea Reszegi et al.
Biomolecules, 10(8) (2020-08-23)
Decorin, the prototype member of the small leucine-rich proteoglycan gene family of extracellular matrix (ECM) proteins, acts as a powerful tumor suppressor by inducing the p21Waf1/Cip1 cyclin-dependent kinase inhibitor, as well as through its ability to directly bind and block
Ting Yao et al.
FEBS open bio, 6(7), 707-719 (2016-07-12)
Decorin (DCN) is a major member of the small leucine-rich proteoglycan (SLRP) family that is critically involved in tumorigenesis and the development of metastasis of cancers, including glioma. Overexpression of DCN was indicated to suppress glioma cell growth. However, the
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