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Merck

P9018

Sigma-Aldrich

佛波醇 12,13-二癸酸佛波醇

solid

别名:

PDD, Phorbol 12,13-dicaprinate

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About This Item

经验公式(希尔记法):
C40H64O8
CAS号:
分子量:
672.93
Beilstein:
6036113
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

solid

顏色

white

溶解度

DMSO: soluble
ethanol: soluble
methanol: soluble

儲存溫度

−20°C

SMILES 字串

[H][C@@]12C=C(CO)C[C@]3(O)C(=O)C(C)=C[C@@]3([H])[C@@]1(O)[C@H](C)[C@@H](OC(=O)CCCCCCCCC)[C@]4(OC(=O)CCCCCCCCC)C2C4(C)C

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一般說明

More potent than phorbol myristate acetate as an inflammatory agent, but weaker as a tumor promoting agent

生化/生理作用

Strong NO promoter; potent activator of protein kinase C; promotes iNOS expression in cultured hepatocytes.

注意

Photosensitive

重構

A stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Hu et al.
The American journal of physiology, 276(2 Pt 2), H488-H495 (1999-02-10)
Both protein kinase C (PKC) and adenosine receptor activation have been shown to enhance ATP-sensitive K+ (KATP) channels. The present studies were designed to determine whether PKC mediates adenosine effects on the KATP channel. The dependence of KATP channel activity
Hiroki Kimura et al.
Schizophrenia bulletin, 41(3), 744-753 (2014-10-22)
Nuclear distribution E homolog 1 (NDE1), located within chromosome 16p13.11, plays an essential role in microtubule organization, mitosis, and neuronal migration and has been suggested by several studies of rare copy number variants to be a promising schizophrenia (SCZ) candidate
Liliana Garneata et al.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 25(1), 67-74 (2014-09-15)
Periodontal disease (PDD) was associated with inflammation, malnutrition, and higher mortality in hemodialysis (HD) patients. Cross-sectional observational study, aiming to assess the prevalence of PDD and the possible relationship among PDD, inflammation, and malnutrition in HD patients. Single HD center
I Magiati et al.
Molecular autism, 6, 40-40 (2015-07-01)
There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely to share common etiology with ASD. A number of measures have been
Leandro Francisco S Bastos et al.
European journal of pharmacology, 576(1-3), 171-179 (2007-08-28)
Tetracyclines induce anti-inflammatory effects unrelated to their antimicrobial activities. We investigated the effect induced by minocycline and doxycycline in models of nociceptive and inflammatory pain, edema, fever, cell migration and formation of fibrovascular tissue, as these effects have not been

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