推荐产品
生物来源
bacterial (Clostridium perfringens)
质量水平
类型
Type I
表单
lyophilized powder
比活
10-50 units/mg protein
组成
protein, 20-40%
环保替代产品特性
Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
应用
diagnostic assay manufacturing
环保替代产品分类
, Enabling
储存温度
−20°C
基因信息
Clostridium perfringens str. 13 ... plc(988262)
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一般描述
我们致力于为您提供更环保的替代产品,以符合“绿色化学的12项原则”的一项或多项原则要求。该产品针对生物柴油研究进行了优化,可提高能效并防止浪费。有关详细信息,请参阅《Biofiles》的文章。
应用
磷脂酶 C (PLC) 已被用于研究肾上腺素受体介导的跨膜信号转导。也用于降解含肌醇的磷脂。此外,它还被用于研究 9E3 基因激活。
生化/生理作用
PLC 水解磷脂酰胆碱和其他甘油磷脂上的磷酸键,生成甘油二酯。这种酶也水解鞘磷脂、心磷脂、胆碱缩醛磷脂和神经酰胺磷脂的磷酸键。磷脂酶 C 受凝血酶和血小板活化因子的诱导,形成 1,2-二酰甘油和磷脂酸。
水解磷脂酰胆碱和其他甘油磷脂的磷酸键生成甘油二酯;该酶也可水解鞘磷脂、心磷脂、胆碱缩醛磷脂以及神经酰胺磷脂的磷酸键。
单位定义
一个单位将在pH 7.3的37 °C下每分钟从蛋黄L-α-磷脂酰胆碱中释放出1.0μmole的水溶性有机磷。
警示用语:
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Mojtaba Alimolaei et al.
Probiotics and antimicrobial proteins, 10(2), 251-257 (2017-04-13)
The alpha-toxin is one of the virulence factors of Clostridium perfringens for gas gangrene in humans and animals or necrotic enteritis in poultry. The C-terminal domain of this toxin ( cpa 247-370 ) was synthesized and cloned into pT1NX vector
R Spangler et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(18), 7017-7021 (1989-09-01)
Induction of the transformation-related gene 9E3 by the v-src and v-fps gene products (v-Src and v-Fps) is blocked in chicken embryo fibroblasts depleted of protein kinase C (PKC). PKC agonists induce 9E3 gene expression. Protein kinase inhibitors block v-Src- and
N Sieger et al.
Arthritis and rheumatism, 65(3), 770-779 (2012-12-13)
CD22 is a surface molecule exclusively expressed on B cells that regulates adhesion and B cell receptor (BCR) signaling as an inhibitory coreceptor of the BCR. Central downstream signaling molecules that are activated upon BCR engagement include spleen tyrosine kinase
Zhou Zhou et al.
Circulation, 127(4), 476-485 (2012-12-26)
Platelet hyperactivity induced by inflammation is a known risk factor for atherosclerosis and thrombosis, but its underlying mechanisms remain poorly understood. The signal transducer and activator of transcription 3 (STAT3) was activated in collagen-stimulated platelets. Activated STAT3 served as a
Jennifer A Woyach et al.
Blood, 123(12), 1810-1817 (2014-01-15)
The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has outstanding activity in patients with chronic lymphocytic leukemia. Most patients experience lymphocytosis, representing lymphocyte egress from nodal compartments. This resolves within 8 months in the majority of patients, but a subgroup has
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