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Merck
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Key Documents

P4107

Sigma-Aldrich

[Leu31, Pro34]-Peptide YY

≥95%

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About This Item

经验公式(希尔记法):
C195H296N54O56
分子量:
4292.76
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.32

品質等級

化驗

≥95%

形狀

powder

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... PYY(5697)

Amino Acid Sequence

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

生化/生理作用

Agonist at Y1, Y4, and Y5 NPY receptors.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Y Dumont et al.
Canadian journal of physiology and pharmacology, 78(2), 116-125 (2000-03-29)
We have evaluated 3 newly developed neuropeptide Y receptor antagonists in various in vitro binding and bioassays: BIBO3304 (Y1), T4[NPY33-36]4 (Y2), and CGP71683A (Y5). In rat brain homogenates, BIBO3304 competes for the same population of [125I][Leu31,Pro34] peptide YY (PYY) binding
M Gobbi et al.
Journal of neurochemistry, 72(4), 1663-1670 (1999-03-31)
125I-[Leu31,Pro34]peptide YY (PYY) and 125I-PYY3-36, initially described as selective neuropeptide Y Y1 and Y2 receptor ligands, respectively, were recently shown to label also Y4 and Y5 receptors. We used receptor autoradiography to assess whether these ligands can be reliably used
L Ferrier et al.
Gut, 46(3), 370-375 (2000-02-15)
Peptide YY (PYY) is involved in the regulation of several gut functions, including secretion and motility. It exerts its effects through a family of six receptors, commonly named the Y receptor family. To characterise the effects of PYY on strips
Ross A Carson et al.
PloS one, 13(5), e0196387-e0196387 (2018-05-09)
Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthesis pathway (CBP), and are used for the prevention of cardiovascular disease. The anti-inflammatory effects of statins may also provide therapeutic benefits and have led to their use in clinical
Xiaohong Yang et al.
Frontiers in bioengineering and biotechnology, 8, 468-468 (2020-06-18)
Effective clinical treatments of cartilage lesions in affected joints require large numbers of viable chondrogenic cells generated through in vivo stimulation or ex vivo expansion of chondrocytes isolated from small biopsy specimens. Conventional passaging of chondrocytes in culture provides sufficient

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