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應用
聚（胞苷肌苷）酸钾盐已用于：
- 进行预处理，用于研究 Con A 诱发的小鼠肝炎
- 血淋巴血浆 RNA 提取，用于 qPCR 检测分析
- 诱导肝脏炎症变化
- 作为刺激虹鳟鱼生殖腺 RTG-2 细胞的基本必需培养基的成分
生化／生理作用
聚（胞苷-肌苷）聚（C，I）是肌苷和胞苷碱的无规共聚物，可用于与其他无规共聚物（例如，Poly（C，A），Poly（C，U）和 Poly （C，G）进行比较理化分析。
聚（胞苷-肌苷）酸，聚 I：C 模仿病毒 RNA 诱导免疫反应。施加 poly I：C 可促进天然杀伤细胞和巨噬细胞的细胞毒性功能。但是，poly I：C 可能会触发抗线粒体抗体（AMA）的产生，并能促进原发性胆汁性肝硬化（PBC）的发病。Poly I：C 可能在 Con A 诱导的 T 细胞依赖性肝损伤中起保肝作用。
其他說明
无规共聚物
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Persistence of double-stranded RNA in insect hemolymph as a potential determiner of RNA interference success: evidence from Manduca sexta and Blattella germanica
Garbutt JS, et al.
Journal of Insect Physiology, 59(2), 171-178 (2013)
G F Joyce et al.
Journal of molecular biology, 188(3), 433-441 (1986-04-05)
Poly(C, G) random copolymer templates direct the oligomerization of 2-Me-ImpG and 2-MeImpC, resulting in the production of a variety of oligo(G, C)s. The efficiency of monomer incorporation into newly synthesized oligomers is greater for 2-MeImpG than for 2-MeImpC, and decreases
G F Joyce et al.
Journal of molecular biology, 176(2), 279-306 (1984-06-25)
Poly(C, U) random copolymer templates direct the oligomerization of 2-MeImpG and 2-MeImpA, resulting in the production of a variety of oligo/(G,A)s. The efficiency of monomer incorporation into newly synthesized oligomers is greater for 2-MeImpG than for 2-MeImpA, and decreases for
G F Joyce et al.
Journal of molecular biology, 202(3), 677-681 (1988-08-05)
Poly(C,A) random copolymer templates direct the oligomerization of 2-MeImpG (2-MeImpX is the 5'-phospho-2-methylimidazolide of the nucleoside X) and 2-MeImpU, resulting in the production of a variety of oligo (G,U)s. This reaction is less efficient than comparable reactions involving poly(C,U) or
The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I: C) and murine autoimmune cholangitis
Wang J, et al.
Journal of Hepatology, 44(3), 446-454 (2006)
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