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Merck

P0048

Sigma-Aldrich

匹莫林

≥98% (HPLC)

别名:

2-氨基-5-苯基 4(5H)-噁唑酮, 苯异妥因

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About This Item

经验公式(希尔记法):
C9H8N2O2
CAS号:
分子量:
176.17
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

solid

藥物控制

USDEA Schedule IV; Home Office Schedule 4.2; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

溶解度

DMSO: 28 mg/mL

起源

Boehringer Ingelheim

儲存溫度

2-8°C

SMILES 字串

NC1=NC(=O)C(O1)c2ccccc2

InChI

1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

InChI 密鑰

NRNCYVBFPDDJNE-UHFFFAOYSA-N

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生化/生理作用

匹莫林为中枢神经兴奋剂。匹莫林用于治疗注意缺陷多动障碍 (ADHD)。匹莫林为第 IV 类精神药品,因其不会造成食欲下降或导致口干而比其他兴奋剂具有优势。

特點和優勢

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges


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A M Muehlmann et al.
Journal of intellectual disability research : JIDR, 56(5), 490-500 (2011-10-13)
Self-injurious behaviour (SIB) is prevalent in neurodevelopmental disorders, but its expression is highly variable within, and between diagnostic categories. This raises questions about the factors that contribute to aetiology and expression of SIB. Expression of SIB is generally described in
Vera Peuckmann et al.
The Cochrane database of systematic reviews, (11)(11), CD006788-CD006788 (2010-11-12)
In healthy individuals, fatigue is a protective response to physical or mental stress, often relieved by rest. By contrast, in palliative care patients fatigue can be severely debilitating, thereby impacting daily activity and quality of life, often with rest not
Philip Shaw et al.
The American journal of psychiatry, 166(1), 58-63 (2008-09-17)
While there has been considerable concern over possible adverse effects of psychostimulants on brain development, this issue has not been examined in a prospective study. The authors sought to determine prospectively whether psychostimulant treatment for attention deficit hyperactivity disorder (ADHD)
Mark Olfson et al.
The Journal of clinical psychiatry, 74(1), 43-50 (2013-02-20)
The authors investigated trends and patterns in stimulant treatment of adults visiting office-based medical practices in the United States. A time series analysis of data from the 1994 to 2009 National Ambulatory Medical Care Surveys (no. of visits = 372,702)
Darragh P Devine
Methods in molecular biology (Clifton, N.J.), 829, 65-84 (2012-01-11)
Self-injurious behaviour is highly prevalent in neurodevelopmental disorders. Interestingly, it is not restricted to any individual diagnostic group. Rather, it is exhibited in various forms across patient groups with distinct genetic defects and classifications of disorders. This suggests that there

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